Dr Justice’s research aims to improve human health through genetics. Genetics and genomics strategies are employed to identify the genetic basis for rare diseases and find rational pathways for therapies. Her current work focuses on a genetic suppressor screen in a mouse model for Rett syndrome, which has identified missing pathway components, new genetic interactions, and unexpected drug targets. Dr. Justice was recruited to SickKids Research Institute as Senior Scientist and Head, Program in Genetics and Genome Biology from Baylor College of Medicine, Houston, Texas, where she was a Professor in the Department of Molecular and Human Genetics and Director of the Mouse Embryonic Stem Cell Core and the NIH-funded Knockout Mouse Program (KOMP2). In fall of 2018, she assumed the role of Scientific Director of The Centre for Phenogenomics in Toronto.A pioneer in mouse mutagenesis, Dr. Justice received her PhD from Kansas State University in developmental genetics, and was a postdoctoral fellow in the Mammalian Genetics Laboratory at the US National Cancer Institute. She is Editor-in-Chief of Disease Models and Mechanisms, and a Senior Editor of Current Protocols in Mouse Biology. She was elected a Fellow of the American Association for the Advancement of Science for her seminal contributions to mouse genetics.