Welcome

Welcome to RE(ACT) – Rare Disease Research Congress, the leading event in rare disease research. From March 10–12, 2027, we will gather in Budapest for three days of inspiring science, meaningful dialogue, and cross-sector collaboration.

Building on the legacy of the RE(ACT) Congress series (now reaching its ninth edition), RE(ACT) continues to serve as a meeting point for scientific innovation and real-world impact. The Congress brings together international leaders, renowned experts, and emerging talents from across disciplines to share breakthrough results, challenge ideas, and help shape the research and policy landscape that will accelerate progress in rare diseases.

True to the spirit of RE(ACT), patients, families, and advocacy organizations are integral to the Congress. Their lived experience strengthens discussions, grounds priorities in unmet needs, and helps ensure that research advances translate into tangible benefits for people living with rare diseases.

Since its launch in 2012, RE(ACT), initiated by the BLACKSWAN Foundation, has promoted scientific exchange and encouraged collaboration in rare and orphan diseases. Working with stakeholders in the rare disease community, RE(ACT) demonstrates a shared commitment to overcoming challenges through collective effort, open collaboration, and knowledge sharing. The 2027 edition is co-organized by the European Rare Diseases Research Alliance (ERDERA) and the International Rare Diseases Research Consortium (IRDiRC), in partnership with EURORDIS (Rare Disease Europe) and Rare Disease International (RDI).

Join us in Budapest as we advance discovery, strengthen partnerships, and build momentum toward a future where rare diseases are no longer barriers—but frontiers we can overcome, together.